Runt-Related Transcription Factor 3 (RUNX3) (C-Term) Peptide
RUNX3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512454
Quick Overview for Runt-Related Transcription Factor 3 (RUNX3) (C-Term) Peptide (ABIN5512454)
Target
RUNX3
(Runt-Related Transcription Factor 3 (RUNX3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RUNX3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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Background
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This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RUNX3,AML2, CBFA3, PEBP2A3,
Protein Size: 415 -
Gene ID
- 864
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UniProt
- Q13761
Target
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